SYRE: Spyre Therapeutics Inc Financial Statements

Balance sheet, income statement, and cash flow statements for Spyre Therapeutics Inc (SYRE).

OverviewDividends

$1.20B Market Cap.

As of 08/06/2025 5:00 PM ET (MRY) • Disclaimer

SYRE Market Cap. (MRY)


SYRE Shares Outstanding (MRY)


SYRE Assets (MRY)


Total Assets

$608.48M

Total Liabilities

$90.68M

Total Investments

$513.66M

SYRE Income (MRY)


Revenue

$0

Net Income

-$208.02M

Operating Expense

$208.57M

SYRE Cash Flow (MRY)


CF Operations

-$157.41M

CF Investing

-$353.29M

CF Financing

$410.91M

SYRE Balance Sheet (MRY)


Metric

2024

2023

2022

2021

Total Assets

$608,484,000 (77.99%)

$341,859,000 (380.52%)

$71,144,000 (-35.28%)

$109,926,000 (-31.98%)

Assets Current

$608,474,000 (78.16%)

$341,528,000 (448.57%)

$62,258,000 (-37.04%)

$98,891,000 (-33.98%)

Assets Non-Current

$10,000 (-96.98%)

$331,000 (-96.28%)

$8,886,000 (-19.47%)

$11,035,000 (-6.71%)

Goodwill & Intangible Assets

$0 (0%)

$0 (0%)

$0 (0%)

$0 (0%)

Shareholders Equity

$517,804,000 (181.39%)

$184,016,000 (265.80%)

$50,305,000 (-40.07%)

$83,941,000 (-39.97%)

Property Plant & Equipment Net

$0 (0%)

$0 (0%)

$6,650,000 (-20.41%)

$8,355,000 (-15.37%)

Cash & Equivalents

$89,423,000 (-52.74%)

$189,215,000 (419.59%)

$36,416,000 (114.46%)

$16,980,000 (-81.53%)

Accumulated Other Comprehensive Income

$180,000 (-40.40%)

$302,000 (729.17%)

-$48,000 (-140.00%)

-$20,000 (-281.82%)

Deferred Revenue

$0 (0%)

$0 (0%)

$2,696,000 (-24.61%)

$3,576,000 (0%)

Total Investments

$513,665,000 (241.57%)

$150,384,000 (621.34%)

$20,848,000 (-73.27%)

$77,986,000 (38.82%)

Investments Current

$513,665,000 (241.57%)

$150,384,000 (621.34%)

$20,848,000 (-73.27%)

$77,986,000 (38.82%)

Investments Non-Current

$0 (0%)

$0 (0%)

$0 (0%)

$0 (0%)

Inventory

$0 (0%)

$0 (0%)

$0 (0%)

$0 (0%)

Trade & Non-Trade Receivables

$0 (0%)

$0 (0%)

$375,000 (-53.99%)

$815,000 (0%)

Trade & Non-Trade Payables

$1,269,000 (-92.74%)

$17,480,000 (2481.98%)

$677,000 (-79.60%)

$3,319,000 (47.25%)

Accumulated Retained Earnings (Deficit)

-$972,432,000 (-27.21%)

-$764,414,000 (-79.60%)

-$425,624,000 (-24.52%)

-$341,809,000 (-23.84%)

Tax Assets

$0 (0%)

$0 (0%)

$0 (0%)

$0 (0%)

Tax Liabilities

$0 (0%)

$0 (0%)

$0 (0%)

$0 (0%)

Total Debt

$0 (0%)

$0 (0%)

$4,629,000 (-8.23%)

$5,044,000 (-7.42%)

Debt Current

$0 (0%)

$0 (0%)

$625,000 (43.35%)

$436,000 (36.68%)

Debt Non-Current

$0 (0%)

$0 (0%)

$4,004,000 (-13.11%)

$4,608,000 (-10.16%)

Total Liabilities

$90,680,000 (23.73%)

$73,288,000 (251.69%)

$20,839,000 (-19.80%)

$25,985,000 (19.27%)

Liabilities Current

$54,060,000 (69.05%)

$31,978,000 (118.19%)

$14,656,000 (-27.24%)

$20,144,000 (22.51%)

Liabilities Non-Current

$36,620,000 (-11.35%)

$41,310,000 (568.12%)

$6,183,000 (5.86%)

$5,841,000 (9.32%)

SYRE Income Statement (MRY)


Metric

2024

2023

2022

2021

Revenues

$0 (0%)

$886,000 (-61.96%)

$2,329,000 (-87.57%)

$18,739,000 (0%)

Cost of Revenue

$0 (0%)

$0 (0%)

$0 (0%)

$0 (0%)

Selling General & Administrative Expense

$45,776,000 (14.59%)

$39,946,000 (40.01%)

$28,531,000 (4.44%)

$27,319,000 (25.07%)

Research & Development Expense

$162,790,000 (81.88%)

$89,504,000 (52.79%)

$58,579,000 (2.65%)

$57,069,000 (-4.31%)

Operating Expenses

$208,566,000 (-14.24%)

$243,189,000 (179.17%)

$87,110,000 (3.23%)

$84,388,000 (3.57%)

Interest Expense

$0 (0%)

$0 (0%)

$0 (0%)

$0 (0%)

Income Tax Expense

$51,000 (296.15%)

-$26,000 (80.88%)

-$136,000 (-196.45%)

$141,000 (0%)

Net Loss Income from Discontinued Operations

$0 (0%)

$0 (0%)

$0 (0%)

$0 (0%)

Consolidated Income

-$208,018,000 (38.60%)

-$338,790,000 (-304.21%)

-$83,815,000 (-27.38%)

-$65,801,000 (18.66%)

Net Income to Non-Controlling Interests

$0 (0%)

$0 (0%)

$0 (0%)

$0 (0%)

Net Income

-$208,018,000 (38.60%)

-$338,790,000 (-304.21%)

-$83,815,000 (-27.38%)

-$65,801,000 (18.66%)

Preferred Dividends Income Statement Impact

$0 (0%)

$0 (0%)

$0 (0%)

$0 (0%)

Net Income Common Stock

-$208,018,000 (38.60%)

-$338,790,000 (-304.21%)

-$83,815,000 (-27.38%)

-$65,801,000 (18.66%)

Weighted Average Shares

$47,027,638 (581.85%)

$6,897,065 (104.59%)

$3,371,231 (28.19%)

$2,629,784 (23.18%)

Weighted Average Shares Diluted

$47,027,638 (581.85%)

$6,897,065 (104.59%)

$3,371,231 (28.19%)

$2,629,784 (23.18%)

Earning Before Interest & Taxes (EBIT)

-$207,967,000 (38.62%)

-$338,816,000 (-303.59%)

-$83,951,000 (-27.86%)

-$65,660,000 (18.83%)

Gross Profit

$0 (0%)

$886,000 (-61.96%)

$2,329,000 (-87.57%)

$18,739,000 (0%)

Operating Income

-$208,566,000 (13.92%)

-$242,303,000 (-185.80%)

-$84,781,000 (-29.14%)

-$65,649,000 (19.43%)

SYRE Cash Flow Statement (MRY)


Metric

2024

2023

2022

2021

Net Cash Flow from Investing

-$353,285,000 (-225.93%)

-$108,393,000 (-290.14%)

$57,008,000 (352.04%)

-$22,619,000 (-197.46%)

Net Cash Flow from Financing

$410,906,000 (13.80%)

$361,077,000 (746.05%)

$42,678,000 (2963.75%)

$1,393,000 (-99.10%)

Net Cash Flow from Operations

-$157,410,000 (-57.55%)

-$99,910,000 (-24.66%)

-$80,144,000 (-49.20%)

-$53,716,000 (29.11%)

Net Cash Flow / Change in Cash & Cash Equivalents

-$99,792,000 (-165.31%)

$152,799,000 (686.16%)

$19,436,000 (125.93%)

-$74,957,000 (-205.30%)

Net Cash Flow - Business Acquisitions and Disposals

$0 (0%)

$18,035,000 (0%)

$0 (0%)

$0 (0%)

Net Cash Flow - Investment Acquisitions and Disposals

-$353,285,000 (-178.39%)

-$126,903,000 (-322.46%)

$57,046,000 (358.76%)

-$22,046,000 (-563.24%)

Capital Expenditure

$0 (0%)

$475,000 (1350.00%)

-$38,000 (93.37%)

-$573,000 (86.61%)

Issuance (Repayment) of Debt Securities

$0 (0%)

-$16,000 (96.17%)

-$418,000 (18.04%)

-$510,000 (-2450.00%)

Issuance (Purchase) of Equity Shares

$243,893,000 (187.07%)

$84,960,000 (97.14%)

$43,096,000 (2164.63%)

$1,903,000 (-98.77%)

Payment of Dividends & Other Cash Distributions

$0 (0%)

$0 (0%)

$0 (0%)

$0 (0%)

Effect of Exchange Rate Changes on Cash

-$3,000 (-112.00%)

$25,000 (123.58%)

-$106,000 (-606.67%)

-$15,000 (-129.41%)

Share Based Compensation

$44,833,000 (74.62%)

$25,675,000 (261.06%)

$7,111,000 (-11.53%)

$8,038,000 (28.48%)

Depreciation Amortization & Accretion

$0 (0%)

$964,000 (-50.92%)

$1,964,000 (-1.85%)

$2,001,000 (23.21%)

SYRE Financial Metrics (MRY)


Metric

2024

2023

2022

2021

Gross Margin

-

100.00% (0.00%)

100.00% (0.00%)

100.00%

Profit Margin

-

-38238.10% (-962.52%)

-3598.80% (-925.01%)

-351.10%

EBITDA Margin

-

-38132.30% (-983.21%)

-3520.30% (-936.30%)

-339.70%

Return on Average Equity (ROAE)

-60.70% (-110.53%)

576.40% (553.50%)

-127.10% (-107.00%)

-61.40% (10.63%)

Return on Average Assets (ROAA)

-42.60% (73.44%)

-160.40% (-68.66%)

-95.10% (-98.54%)

-47.90% (17.84%)

Return on Sales (ROS)

-

-38241.10% (-960.90%)

-3604.60% (-928.71%)

-350.40%

Return on Invested Capital (ROIC)

-62.00% (-101.02%)

6106.20% (3273.70%)

-192.40% (-130.42%)

-83.50% (27.01%)

Dividend Yield

0% (0%)

0% (0%)

0% (0%)

0% (0%)

Price to Earnings Ratio (P/E)

-7.32 (-368.09%)

-1.56 (-246.02%)

-0.45 (90.48%)

-4.75 (8.34%)

Price to Sales Ratio (P/S)

-

167.52 (928.94%)

16.28 (-2.30%)

16.66

Price to Book Ratio (P/B)

2.31 (387.76%)

0.47 (-13.82%)

0.55 (-80.29%)

2.79 (3.45%)

Debt to Equity Ratio (D/E)

0.17 (-56.03%)

0.4 (-3.86%)

0.41 (33.55%)

0.31 (98.72%)

Earnings Per Share (EPS)

-3.18 (76.89%)

-13.76 (44.65%)

-24.86 (0.64%)

-25.02 (34.16%)

Sales Per Share (SPS)

0 (0%)

0.13 (-81.48%)

0.69 (-90.30%)

7.13 (0%)

Free Cash Flow Per Share (FCFPS)

-3.35 (76.78%)

-14.42 (39.38%)

-23.78 (-15.21%)

-20.64 (44.95%)

Book Value Per Share (BVPS)

11.01 (-58.73%)

26.68 (78.80%)

14.92 (-53.25%)

31.92 (-51.27%)

Tangible Assets Book Value Per Share (TABVPS)

12.94 (-73.90%)

49.57 (134.88%)

21.1 (-49.51%)

41.8 (-44.78%)

Enterprise Value Over EBIT (EV/EBIT)

-5 (0%)

0 (0%)

0 (0%)

-3 (25.00%)

Enterprise Value Over EBITDA (EV/EBITDA)

-5.41 (-38764.29%)

0.01 (-85.86%)

0.1 (102.96%)

-3.35 (18.87%)

Asset Turnover

0 (0%)

0 (-84.62%)

0.03 (-80.88%)

0.14 (0%)

Current Ratio

11.26 (5.39%)

10.68 (151.41%)

4.25 (-13.47%)

4.91 (-46.11%)

Dividends

$0 (0%)

$0 (0%)

$0 (0%)

$0 (0%)

Free Cash Flow (FCF)

-$157,410,000 (-58.30%)

-$99,435,000 (-24.01%)

-$80,182,000 (-47.69%)

-$54,289,000 (32.19%)

Enterprise Value (EV)

$1,125,738,802 (23719.75%)

-$4,766,091 (41.15%)

-$8,098,166 (-103.80%)

$212,928,800 (-34.85%)

Earnings Before Tax (EBT)

-$207,967,000 (38.62%)

-$338,816,000 (-303.59%)

-$83,951,000 (-27.86%)

-$65,660,000 (18.83%)

Earnings Before Interest Taxes & Depreciation Amortization (EBITDA)

-$207,967,000 (38.44%)

-$337,852,000 (-312.08%)

-$81,987,000 (-28.79%)

-$63,659,000 (19.69%)

Invested Capital

$465,001,000 (285.36%)

$120,666,000 (388.51%)

$24,701,000 (-68.27%)

$77,846,000 (32.65%)

Working Capital

$554,414,000 (79.10%)

$309,550,000 (550.29%)

$47,602,000 (-39.55%)

$78,747,000 (-40.95%)

Tangible Asset Value

$608,484,000 (77.99%)

$341,859,000 (380.52%)

$71,144,000 (-35.28%)

$109,926,000 (-31.98%)

Market Capitalization

$1,197,318,802 (1274.13%)

$87,132,909 (214.86%)

$27,673,834 (-88.19%)

$234,269,800 (-37.90%)

Average Equity

$342,962,000 (683.51%)

-$58,775,750 (-189.16%)

$65,918,500 (-38.51%)

$107,200,250 (-8.99%)

Average Assets

$488,310,500 (131.12%)

$211,276,500 (139.69%)

$88,146,750 (-35.84%)

$137,395,750 (-0.97%)

Invested Capital Average

$335,591,000 (6148.05%)

-$5,548,750 (-112.72%)

$43,628,000 (-44.54%)

$78,672,250 (11.23%)

Shares

51,431,220 (1170.24%)

4,048,927 (64.56%)

2,460,443 (24.72%)

1,972,798 (2.88%)